Two men were left needing hospital treatment after they were attacked by three men in Fishermead.
The incident happened in Pencarrow Place at around 11.25pm on Friday.
The victims, two men aged 26 and 25, were attacked by three men after a short altercation.
The 26-year-old man suffered a cut to his arm and the 25-year-old man had two front teeth knocked out.
The main offender is white, around 5ft 6ins tall, in his late twenties or early thirties with a slim build and mousy coloured short hair. He was wearing a white T-shirt and blue jeans. One of the other offenders is white, 6ft, with a large build and short mousy brown hair. He was wearing a white top.
Anyone with any information about this incident should contact PC Martin Connor, at Milton Keynes police station, via 0845 8 505 505.
Alternatively, if you do not want to speak to police or leave your name, please contact the Crimestoppers charity on 0800 555 111.