Highways England have announced new road closures to begin at the start of next week.
Some lanes of the A5 will be closed while the safety barriers are repaired.
The work will be undertaken on weekdays between 8pm and 6am to minimise disruption and should be completed early December.
Some full closures are required to install temporary barrier and road markings and a clearly signed diversion route will be in place when the road is closed.
The speed limit will be reduced to 50mph past the works and this will remain in place during the day.
In addition while both lanes of the A5 will be open during the day, they will have to be narrowed.
On Monday, November 28 the A5 northbound will be closed between A421 Redmoor Roundabout (H9) and A422 Abbey Hill Roundabout (H3).
Drivers will be diverted to take V6 to re-join the A5 northbound via the A422 Abbey Hill Roundabout (H3).
On Tuesday, November 29 the A5 northbound will be closed between A421 Redmoor Roundabout (H9) and A508 Old Stratford Roundabout.
Drivers will be diverted to take V6, A422 Monks Way, Great Monks St (V5), Stratford Rd, Queen Eleanor St, London Rd and Towcester Rd to re-join the A5 at A508 Old Stratford Roundabout.
From Wednesday, November 30 we will be working on the A5 northbound between the A422 Abbey Hill Roundabout (H3) and A508 Old Stratford Roundabout.
The left hand lane is closed while we are working and a 50mph speed limit is in place.