People living on the up-market Middleton estate can expect to live up to 11 years longer than people a few miles away on Netherfield or Beanhill.
The shock statistic was revealed this week in the latest social atlas report on Milton Keynes.
Other longevity areas were shown to be Newport Pagnell, Olney, Woburn Sands and Hanslope, all of which have the least social deprivation.
The worst area was Woughton ward, which includes Netherfield, Beanhill, Eaglestone, Tinkers Bridge and Leadenhall.
People born on these estates can expect to live for 75.4 years, compared to 86.3 years in Middleton, according to the social atlas
The national average life expectancy is 79.2 years for males and 83 years for females. Milton Keynes as a whole is marginally below these figures with 78.7 years and 82.5 years respectively,
The 146-page social atlas also gives an insight into everything from crime figures to educational achievements in every area of the city.
It scores each estate or town with ‘social exclusion’ indicators, highlighting what percentage of residents claim benefits, have special educational needs or disabilities, suffer crimes or complain about their neighbourhood.
It even shows how many people attend the hospital’s Accident & Emergency department each year – 42 per cent in the case of Beanhill.
The report reveals crime has reduced throughout MK – though figures are still higher than the regional average.