Customers for businesses on an estate road in Bletchley will have to take an alternative route from June 29.
The westbound carriageway of Dawson Road, on Mount Farm, will be closed at its junction with the V7 Saxon Street until August 22.
The closure is designed to reduce congestion on the V7 while work takes place to build a new access road for stadiummk.
Drivers will be asked to use an alternative route via the eastbound carriageway of Dawson Road, Bond Avenue, H10 Bletcham Way and V7 Saxon Street.
There will be controlled access to premises along Dawson Road.