Thames Valley Police is appealing for witnesses to a serious injury collision which happened just outside Winslow.
The incident happened on the B4033 Great Horwood Road at around 6pm on Wednesday.
A black Peugeot 308 GT and a blue Mazda 323, believed to be travelling in opposite directions, were involved in a collision on a bend.
The driver of the Peugeot, a 46-year-old woman, was taken to Milton Keynes General Hospital with minor injuries and was kept in overnight for observations. The driver of the Mazda, a 44-year-old woman, was taken to the JR2 Hospital with life changing injuries and the passenger from that car, a 21-year-old woman, was taken to Milton Keynes General Hospital with a serious facial fracture.
Anyone with any information about this collision should contact PC Rob Lyne, at the Three Mile Cross roads policing base via the Force Enquiry Centre on 101. If you don’t want to speak directly to the police you can contact the independent charity Crimestoppers anonymously on 0800 555 111 or online at crimestoppers-uk.org.