Matt Dennis opened the scoring in the first-half, and Dons had plenty of chances to put the game to bed before the break, but Jimmy-Jay Morgan’s equaliser threatened to upset the apple cart.
Jonathan Leko though restored Dons’ lead early in the second-half before Max Dean came off the bench to score a brace to complete the win.
1. How MK Dons rated against Chelsea U21s on Tuesday night
There were plenty of promising performances in the 4-1 win in the EFL Trophy - here's how we ranked them at Stadium MK Photo: Jane Russell
2. Nathan Harness - 6.5
A decent debut between the sticks from Harness. A couple of good saves, mixed with a couple of heart-in-mouth moments too, but overall a solid outing Photo: Jane Russell
3. Dean Lewington - 6.5
A good return from injury. Not really given much trouble by the Chelsea youngsters before coming off after an hour Photo: Jane Russell
4. Jack Tucker - 7
Held firm in the centre of the defence alongside returning Lewington and youngster Tripp. Photo: Jane Russell