Firefighters attended a fire in what is believed to be the former Wolverton Town sports and social club building.
At approximately 7.55am, Buckinghamshire Fire and Rescue Service attended the blaze on Field Lane, Greenleys.
One crew from Great Holm and one from Broughton attended.
Firefighters used cutting equipment to gain entry, two hose reels, two sets of breathing apparatus and a pressure ventilation fan.
The cause is being investigated.