The emergency services are attending a crash between two vehicles on the A422 between Milton Keynes and Buckingham.
The crash happened during rush hour this morning (Friday) and police have currently closed a stretch of the A422 between Maids Moreton and the Stratford Road roundabout.
The incident on Stratford Road involved a car and a lorry and firefighters at the scene have released an injured man from a car.
South Central Ambulance Service, who are also at the scene, have described the crash as 'serious' and say that the road is likely to be closed for a 'significant amount of time.'
Police are urging the public to avoid the area and find an alternative route.
More on this as we get it.