Hardmead Bridge is to undergo refurbishment, which could mean chaos for motorists throughout August and September.
Temporary traffic lights will be put in place to prevent travel on the north side of the bridge - A422 East bound from Chicheley to Bedford.
The work is planned to last for eight to ten weeks throughout August and September.
A single lane will be kept open over the bridge at all times using 24 hour operated two-way temporary traffic lights.
A motorist who regularly uses the bridge, said: “This must impact thousands of people a day and it could go on until November.
“The joke is in the summer months when it’s easier to fix - nothing is happening.”
For more information visit www.milton-keynes.gov.uk/streets-transport-and-parking/roads-highways-and-pavements/bridges-underpasses