Josh McEachran limped out of the game at the Abbey Stadium in the first half which could open the door for a change in the centre of the park, while we predict there may also be a change on the right flank.
Here’s how we think MK Dons will line-up for the first match back at Stadium MK.
5. LB - Dean Lewington (c)
Back in his old position again, the skipper will almost certainly retain his place Photo: Jane Russell
6. CM - Matt Smith
The best player on the park for Dons last week. His creativity will be key again against Wednesday Photo: Jane Russell
7. CM - Ethan Robson
With injury to McEachran last week, Robson could be a like-for-like replacement in the centre of the park to make his second debut for the club after moving from Blackpool in the summer Photo: Jane Russell
8. AM - Conor Grant
Barely got a kick at Cambridge to show what he is about, but remains in line to take on his former club Photo: Jane Russell