Will Grigg and Nathan Holland are both set to miss out after suffering injuries against the Owls, while we predict Liam Manning may make some other changes too.
Here’s how we predict Dons will line-up tonight.
. MK Dons v Sheffield Wednesday JAR_2775.JPG
Matt Dennis is set to make his first start for MK Dons Photo: Jane Russell
. GK - Franco Ravizzoli
Used in the cup competitions last season, Ravizzoli could come in to replace Jamie Cumming between the sticks Photo: Jane Russell
. LB - Henry Lawrence
After a patchy start against Cambridge, Lawrence should get another chance to show what he is about, while also offering Dean Lewington a chance to put his feet up Photo: Jane Russell
. CB - Jack Tucker
Forming a good relationship with Warren O'Hora, is likely to keep his place Photo: Jane Russell
. CB - Warren O'Hora
Mr Reliable for MK Dons at centre back Photo: Jane Russell
. RB - Daniel Oyegoke
After a promising performance against Sheffield Wednesday, should keep his place in the side Photo: Jane Russell
1. GK - Franco Ravizzoli
Used in the cup competitions last season, Ravizzoli could come in to replace Jamie Cumming between the sticks Photo: Jane Russell
2. LB - Henry Lawrence
After a patchy start against Cambridge, Lawrence should get another chance to show what he is about, while also offering Dean Lewington a chance to put his feet up Photo: Jane Russell
3. CB - Jack Tucker
Forming a good relationship with Warren O'Hora, is likely to keep his place Photo: Jane Russell
4. CB - Warren O'Hora
Mr Reliable for MK Dons at centre back Photo: Jane Russell