The sides are locked together on the same points in 22nd and 23rd in the table, and while a win will not lift either out of the bottom four, it would go a long way towards helping the cut the gap to safety which currently stands at four points.
Dons suffered another blow this week with the suspension of Zak Jules for violent conduct – an incident not spotted by match officials during the 1-0 defeat to Port Vale last weekend, but picked up on video evidence.
With Warren O’Hora and Anthony Stewart out injured, and Dean Lewington closing in on full fitness but having missed the last three-and-a-half months, Jackson may have to experiment with his back line due to sheer lack of numbers.
He also hinted last week at chances to his front line after his regulars have misfired in recent games, while his second-half substitutions have made impacts when brought on.
Here’s how we think Dons will line-up at Stadium MK.