Despite a strong opening 45 minutes, Dons went in level after Anthony Scully’s penalty cancelled out Stephen Wearne’s opener - the first goal on the road this season for Mike Williamson’s side.
A Fiacre Kelleher strike nine minutes after half-time then secured the points for Colchester.
Here’s how we rated the players
5. Joe Tomlinson - 6.5
Popped up on the right flank after spending all season on the left. Always looked eager to take on his man | Jane Russell
6. Top Don: Brooklyn Ilunga - 7
Really good, especially in the first-half. Gave a constant option, came close with a strike too. | Jane Russell
8. Liam Kelly - 6
Helped Dons play some decent stuff in the first-half especially, picking up a lot of close-quarter positions | Getty Images
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