With questions about the formation, the midfield options and who will lead the line, the head coach could go with a similar looking side to the one which started against Barnet last Saturday in their final pre-season friendly.
Here, we have a go at guessing how Dons will line-up at the Abbey Stadium.
9. RW: Louie Barry
The Villa loanee can play through the middle as well, but in the Dons system will be able to cut in from the right to add to the attack Photo: HANNAH MCKAY
10. LW: Nathan Holland
The former West Ham man adds natural width to the side, and could fizz some dangerous balls into the mixer Photo: Pete Norton
11. ST: Will Grigg
A Dons player at last, Grigg is set to lead the way for the opening day of the season, looking to build on his 30 goals scored in two previous loan spells Photo: MK Dons
12. Option: Bradley Johnson
Offers vast experience in the midfield, and could be used off the bench to help see a game out or to spark something a bit different Photo: MK Dons